
The Benefits of Polynucleotides & Exosomes
Polynucleotides and Exosomes represent some of the most exciting innovations in aesthetic medicine, though their regenerative properties have been studied in scientific and medical fields for decades. Polynucleotides support skin repair, hydration, and elasticity by working at a cellular level, while Exosomes act as powerful messengers that stimulate renewal, repair, and protection processes within the skin.
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Together, they offer a synergistic approach to rejuvenation, helping to improve texture, tone, and resilience in a way that goes beyond the effects of many traditional aesthetic treatments.
Unlocking the Benefits of Polynucleotides
Polymeric macromolecules result in an immediate “scavenger” action against free radicals. It is this ability to inhibit free radicals which is so important and the reason to look to a treatment based on polynucleotides.
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The chemical structures of the nitrogenous ring on the polynucleotides immediately react with free radicals, which neutralises them. When the polynucleotides molecule is being degraded by the body's enzymes, smaller particles retain the same properties as the whole Polynucleotide molecule. This process plays a protective and cell damage reduction role by counteracting the skin damage that can build as a result of numerous stressors, such as cellular damage, sun damage and stress.
Forbes reports that 'Polynucleotides, often derived from salmon as studies have shown that salmon DNA is very similar to those of human, also support the reduction of dark circles and fine lines, restoring skin tone, supporting acne scaring, and even neutralizes free radicals. Dr Marwa Ali, celebrity aesthetic doctor at Harrods Wellness Clinic explains
“Long-term, the treatment will help to slow down the aging process by activating your cell receptors and preserve your own natural skin tissue, which will result in longer lasting great skin quality and more youthful looking skin. I would recommend Ameela [polynucleotides] to anyone that may be concerned about ageing or skin concerns."
The right treatment for the right results
Polynucleotide treatments offer a wide range of benefits, with natural-looking improvements often visible from the very first session. For longer-lasting effects, a course of 2–3 treatments is typically recommended, with maintenance sessions helping to preserve results over time.
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By tailoring the treatment approach to individual needs, practitioners can address concerns such as eye bags, dark circles, fine lines, acne scarring, hyperpigmentation, stretch marks, and dehydrated skin. The versatility of polynucleotides means they can be adapted for different treatment areas and patient goals, supporting both restorative and preventative skin health.
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Using the correct protocol is key to achieving the best outcomes, ensuring each treatment is optimised for its intended indication.

